Glen research/2’-OMe-U-Thiophosphoramidite/1kit/10-3173-02
商品编号：
10-3173-02
品牌：
Glenresearch
市场价：
¥14400.00
美元价：
8640.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Technical Documents
Description
Details
Dilution/Coupling Data
Technical Documents
Description
The phosphorodithioate linkage (PS2) is both achiral and essentially resistant to nucleases. Previous studies have shown very interesting results which include observations that DNA with PS2 linkages activates RNase H , strongly inhibits human immunodeficiency virus (HIV) reverse transcriptase, induces B-cell proliferation and differentiation, and is completely resistant to hydrolysis by various nucleases.2’-OMe- RNA Thiophosphoramidites are RNA monomers designed to produce oligos combining the PS2 linkage with the 2’-O-methyl ribose modification.These PS2-modified RNA oligos have potential for use in siRNAs and dithiophosphate aptamers (thioaptamers).
Details
Usage
- Coupling: See Technical Bulletin
- Deprotection: See Technical Bulletin for details (http://www.glenresearch.com/Technical/TB_Thioamidites2015.pdf).
| Specifications | |
|---|---|
| Diluent | 10% DCM in Acetonitrile |
| Storage | Freezer storage, -10 to -30°C, dry |
| Stability | Use Immediately |
Dilution/Coupling Data
The table below show pack size data and, for solutions, dilution and approximate coupling based on normal priming procedures.
ABI 392/394
| Catalog # | Pack Size | Grams/Pack | 0.1M Dil. (mL) | Approximate Number of Additions | |||||
|---|---|---|---|---|---|---|---|---|---|
| LV40 | LV200 | 40nm | 0.2μm | 1μm | 10μm | ||||
| 10-3173-02 | 0.25 g | .25grams | 1.94 | 51.33 | 30.8 | 19.25 | 14 | 10.27 | 2.57 |
| 10-3173-90 | 100 µmol | .086grams | 0.67 | 9 | 5.4 | 3.38 | 2.45 | 1.8 | 0.45 |
Expedite
| Catalog # | Pack Size | Grams/Pack | Dilution (mL) | Approximate Number of Additions | ||||
|---|---|---|---|---|---|---|---|---|
| Molarity | 50nm | 0.2μm | 1μm | 15μm | ||||
| 10-3173-02 | 0.25 g | .25grams | 2.9 | 0.1 | 51.6 | 32.25 | 23.45 | 3.23 |
| 10-3173-90 | 100 µmol | .086grams | 1 | 0.1 | 13.6 | 8.5 | 6.18 | 0.85 |
Related Products
Related Products
2"-OMe-A-ThiophosphoramiditeCatalog #: 10-3170
2’-OMe-C-ThiophosphoramiditeCatalog #: 10-3171
2’-OMe-G-ThiophosphoramiditeCatalog #: 10-3172
dT-ThiophosphoramiditeCatalog #: 10-1730
Sulfurizing Reagent IICatalog #: 40-4037
品牌介绍
Glen research对我们的员工，我们的客户和环境的承诺Maravai LifeSciences致力于在所有业务活动中成为环境，健康与安全（EHS）管理方面的领导者，符合Maravai LifeSciences的商业利益和行为准则。我们承诺：雇员我们将通过提供零伤害的工作场所来预防伤害和疾病并促进健康的生活方式，从而对每位员工产生积极影响。我们将确保我们的员工具有执行此政策的意识，工具和知识。可持续发展我们将通过使用确保安全，效率和社会责任的商业惯例，以现在和将来保护我们的员工，社区，股东和环境的方式，进行可持续思考和采取行动。合规我们将遵守适用的法律和法规，同时提供程序和程序以确保我们的遵守。文化我们将通过停工授权，查明根本原因并采取纠正措施，倡导一种不容忍不安全状况和行为的文化。业务整合我们会将环境，健康和安全考虑因素纳入我们的业务活动。顾客我们将与客户紧密合作，以帮助他们满足其环境，健康和安全需求。供应商和承包商我们将与我们的供应商和承包商合作，以改善环境，健康和安全绩效。社区与政府我们将参与社区和政府的环境，健康和安全计划。这些价值观得到了Maravai高层管理人员的重视，并在组织内的所有责任级别得到强调。卡尔·赫尔（Carl Hull）首席执行官
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